The research remits of the Lipidomics and Nutrition Research centre are to unravel the role of lipids and antioxidant nutrients in growth and development and genetic (sickle cell disease) and non-genetic chronic diseases (diabetes, epilepsy, multiple sclerosis, autism spectrum disorder and attention deficit hyperactivity disorder for example).
The medium and short term aims are to investigate:
- The therapeutic potential of omega-3 and -6 fatty acids and vitamin D for chronic disease and elucidate mechanisms.
- How receptor function and signalling, cognitive function and behaviour are affected by changes in membrane lipid composition.
- Magnetic resonance imaging of brain pathology in patients with chronic diseases.
- Placental fatty acid receptor and transporter protein function and dysfunction in pregnancy and foetal development.
- The effect of saturated and unsaturated fatty acids on the insulin action of hypothalamic neurons.
- Fatty acids and related lipid mediators and their role in immune function, and autoimmune and inflammatory disorders.
Between 2014 and 2021, the research centre has conducted successfully basic and translation investigations in collaborations with nine international and seven national institutions, published peer-reviewed (23) and international conference (33) publications, hosted international visiting researchers:
- Madu A MD, University of Nigeria, Enugu, May-August 2015
- Ibrahim FI MD, University of Khartoum, Sudan, February-July 2016
- Oghagbon EK MD, Benue State University, Makurdi, October 2015-April 2016
To enhance and broaden the lipidomic research pertaining to nutrition, pre- and post-natal growth and development, optimal health, and neuro-visual and vascular dysfunction induced by chronic and genetic disorders.
To undertake basic and applied research primarily on lipid and membrane biochemistry in relation to development and health.
Events and seminars at the Lipidomics and Nutrition Research Centre
Latest research news
When objects in space collide
Dr Jon Tandy discussed his research on the processes that happen in high-speed collisions in solar systems on the Science Off Camera podcast.
Reducing malnutrition in children undergoing chemotherapy
A London Met-GOSH study aimed to find out how different types of feeding affected the weight of children experiencing mucositis as a result of chemotherapy.
3D printing for drug delivery
Dr Bruno Sil dos Santos uses 3D printing to develop new surrogates that can mimic the same properties as human membranes to find new ways to improve approaches to drug delivery.
Fighting a near-impossible fight: using antibodies to eradicate viruses
Gary McLean, Professor in Molecular Immunology, explains his life’s work to find and use monoclonal antibodies to target viruses.