Prostate Cancer Research Theme Cellular Molecular and Immunology Research Centre

Prof Chris Palmer (Lead)
Dr Una Fairbrother
Dr Samireh Jorfi

E Kidd (PhD student)
M Kaleta (PhD student)
Xin Yu (PhD student)
Eliz Arter (PhD student)

Our projects include:

1. Inhibition of microvesiculation to limit drug efflux in prostate cancer. This is coupled to another project on using microvesicles (including those derived from stem cells) as targeted drug delivery vehicles in cancer research.
2. Use of prostate cancer-targeted microvesicles delivering both chemotherapeutic drug and inhibiting subsequent microvesiclation.
3. The role of microvesicles in EMT transdifferentiation in prostate cancer.
4. HPV/EBV and microvesicles in prostate cancer.
5. Microvesicles and complement inhibiting peptides that break tolerance by inhibiting iC3b-CR3 interaction, thus allowing maturation of dendritic cells; Novel immunotherapeutic approaches in prostate cancer therapy.
6. Transdifferentiation and dedifferentiation in monocytic leukaemia.